PhD in structural biology

A 4-year position is available for a PhD candidate in the research group of Dimphna Meijer, Department of Bionanoscience, Delft University of Technology, the Netherlands./nProject focus: cryo-EM/ET imaging of reconstituted synapses and bottom-up structural characterization of synapse assembly using cryo-electron tomography (cryo-ET) and complementary light microscopy methods./nSpecific objectives are: Setting up cryo-ET FIB SEM workflow for reconstituted synapses; Visualize nanoscale architecture of reconstituted synapses; High-resolution structure determination of synaptic CAM pairs; Confirmative structure-function studies in primary neurons./nState-of-the-art equipment, including high-end light and (cryo-)electron microscopes, as well as advanced mammalian cell culture facilities, are available in the department./nLocation: Delft, the Netherlands.