PhD in Exercise Physiology

Background:/nThe impact of diet on mental health and brain performance is a topic of growing focus and concern: diets rich in saturated fats have been associated with a significant risk for cognitive decline later in life, whilst healthier diets, rich in plant polyphenols are linked to reduced risk of dementia./nWe have shown that foods rich in flavonoids can prevent negative effects of stress on vascular function both when administered in isolation and in the context of a high-fat meal. Intake of flavonoids before physiological stress also results in higher and faster levels of cerebral oxygenation in the pre-frontal cortex and better cognitive performance in young healthy individuals./nObjectives:/nIn this project, our key objectives are to investigate whether single and habitual intake of polyphenols with the diet improve brain oxygenation and arterial function in the context of stress, leading to better cognitive performance and improved mood in middle-aged healthy adults. These data will establish whether dietary polyphenols are effective to minimize the impact of stress on mood and cognitive function, by modulating the underlying physiological responses to stress. We will also identify individuals who may benefit the most from incorporation of polyphenols into their diet during stressful periods./nLocation: Birmingham