PhD in Chemistry

PhD student in Biochemistry Structure and dynamics of photoreceptor proteins using novel methods in time-resolved structural biology. Department of Chemistry for Life Sciences conducts research and education in analytical chemistry, biochemistry and organic chemistry. More than 100 people, including around 45 PhD students, work at the department. New employees and students are recruited from all over the world and English is the main working language. The department is located at the Biomedical Centre in Uppsala, which facilitates collaborations with research groups in biology, pharmacy, medicine and SciLifeLab and gives access to advanced infrastructure for experimental and theoretical studies. The international environment and good opportunities for interdisciplinary collaborations enables PhD students at the department to participate in relevant research projects and prepare for an international research career. Project description We are looking for a PhD student for studying structural changes of photoreceptor proteins using time-resolved diffraction methods. A concrete goal will be to structurally characterize the structural effects of charge transfer (for example in cryptochrome and photolyase proteins) using time-resolved serial femtosecond crystallography at Free-electron laser sources. The project requires production and crystallization of protein, performance of time-resolved crystallography experiments at Free electron laser sources, and advanced data analysis of the time-resolved crystallographic data in terms of structure and dynamics. You are expected to be involved in all steps of this collaborative project, however, depending on your background and interest the emphasis of your work will be adapted. You will be required to work at the forefront of the method and develop it further, both in terms of performing the experiment and on the data analysis side.