PhD in Biophysics

Are you curious about the fundamental molecular changes that occur during ageing and disease? Utrecht University offers a PhD position on the role of macromolecular crowding in ageing and neurodegenerative diseases, studied in the model organism C. elegans. The living cell is highly crowded with macromolecules such as proteins and nucleic acids. Proteins are continuously at risk of aggregation, which is a hallmark of ageing and of many human neurodegenerative diseases. The group of Dr Tessa Sinnige at the Bijvoet Centre for Biomolecular Research investigates the molecular mechanisms of protein aggregation in vivo, using the nematode C. elegans as a multicellular model organism.